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The haemoglobin binding of five nitroarenes — i.e., nitrobenzene, 4-nitrobiphenyl, 1-nitropyrene, 2-nitronaphthalene and 2-nitrofluorene — and their corresponding amines, administered orally to male SD rats, was determined by HPLC to evaluate the extent of in vivo reductive and oxidative activations of these compounds to N -hydroxylamines, which covalently bind to haemoglobin to form acid-labile sulfinamides (Suzuki et al., 1989)

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doi: 10.4103/0973-1482.235342 [DOI] [PubMed] [Google Scholar] 35.Liu J, Yu L, Castro L, et al