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Strength-of-evidence judgments within each evidence stream were made using standard terminology (eg, robust, moderate, slight, indeterminate, compelling evidence of no effect) and criteria from the IRIS Handbook, which adapts Hill's causality criteria to evaluate several factors, such as study quality, consistency across studies, dose-response relationships, strength of association, outcome directness, and coherence of findings
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Glutathione as a signaling molecule: another challenge to pathogens