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This ecological framing aligns with the broader therapeutic utility of fungal secondary metabolites, including antibiotics, antifungals and immunosuppressants, derived from the same biosynthetic machinery, suggesting that the distinction between mycotoxins and pharmaceuticals reflects producer organism and exposure context rather than chemical mechanism ( The ecological and metabolic continuum of mycotoxins extends beyond ingestion, as dietary mycotoxins encounter the gut microbiota, a highly dynamic metabolic interface that shapes xenobiotic transformation and consequently modulates mycotoxin bioavailability, toxicity and host exposure (Li et al., 2025)