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Inflammatory Stress-Induced CKD During the inflammation process, germline-encoded pattern recognition receptors (PRRs) work as the main host devices that identify the varieties of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs), and PPR activation generally triggers the stimulation of toll-like receptors (TLRs) as well as intracellular nod-like receptors (NLRs)