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−/− ;IL-10 −/− mice) • Winnie mice (Muc2 mutation): Genetic model of chronic epithelial barrier defect-driven ulcerative colitis ( 102 )

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Decreased anti-oxidant activity of CAT, GSH-Px, GST, and levels of low-molecular-weight anti-oxidants, vitamin C and vitamin E, and GSH were observed in STZ-treated rats, while TBARS and hydroperoxides (lipid peroxidation markers) increased