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doi: 10.3390/proteomes11040037, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 454

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Slightly higher levels of radioactivity (0.2–1.0%) accumulated in the liver and kidneys, but most extraintestinal tissues showed a rapid decline in EC levels to below 0.1% within 24 h post-administration, and further reductions were observed by 48 h ( 2.1.2.3 Metabolism The metabolism of EC plays a pivotal role in determining its overall bioavailability and biological activity