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Studies have shown that sodium acetate, sodium butyrate, and sodium propionate can significantly inhibit the activation of the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway, reduce the production of reactive oxygen species (ROS), and block the NLRP3/Caspase-1 axis, thereby exerting broad anti-inflammatory effects (Yi et al., 2022)