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Moreover, with the expression of CD73 and CD39, Treg cells catalyze ATP to adenosine, which inhibits the function of effector T cells (Vignali et al., 2008)

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however, this induction does not appear to fully depend on p53 status, as p53 knockout only led to a partial rescue of cell death in response to methionine deprivation [8,17,52]

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