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In addition, at the therapeutic doses, no significant immune response was induced by GNC–siRNA group, as the production of serum cytokines, including interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α) was similar to the saline control group (Supplementary Fig

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The relationship between TNF-α and spike protein was monitored in both treated and untreated PBMCs